Systematic protein–protein interaction mapping for clinically relevant human GPCR s
نویسندگان
چکیده
منابع مشابه
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
G-protein-coupled receptors (GPCRs) are the largest family of integral membrane receptors with key roles in regulating signaling pathways targeted by therapeutics, but are difficult to study using existing proteomics technologies due to their complex biochemical features. To obtain a global view of GPCR-mediated signaling and to identify novel components of their pathways, we used a modified me...
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ژورنال
عنوان ژورنال: Molecular Systems Biology
سال: 2017
ISSN: 1744-4292,1744-4292
DOI: 10.15252/msb.20167430